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Nature

TechnologyNature·Aug 5, 2026·1 min read

DCAF11-dependent molecular glue degrader activated by glutathionylation

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10873-1 M12 is a metabolically activated molecular glue that recruits diverse proteins to DCAF11 for ubiquitin-mediated degradation, revealing a glutathione-dependent…

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